Drugs to Treat Neurological Damage tagged posts

Synthetic Compound could serve as Prototype for Novel Class of Drugs to Treat Neurological Damage

CPTX (orange) combines functional domains present in synaptic organizing proteins in a unique way. The compound was designed to act as a universal buridge builder for excitatory connections between nerve cells. Source: DZNE/Alexander Dityatev

Researchers from the German Center for Neurodegenerative Diseases (DZNE), UK and Japan have developed a neurologically acting protein and tested it in laboratory studies. In mice, the experimental compound ameliorated symptoms of certain neurological injuries and diseases, while on the microscopic level it was able to establish and repair connections between neurons. This proof-of-principle study suggests that biologics, which act on neuronal connectivity, could be of clinical use in the long term. The results are published in the journal Science.

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