EBV tagged posts

The role that Epstein-Barr virus (EBV) plays in the development of multiple sclerosis (MS) may be caused by a higher level of cross-reactivity, where the body’s immune system binds to the wrong target, than previously thought.

In a new study published in PLOS Pathogens, researchers looked at blood samples from people with MS, as well as healthy people infected with EBV and people recovering from glandular fever caused by recent EBV infection.

The study investigated how the immune system deals with EBV infection as part of worldwide efforts to understand how this common virus can lead to the development of multiple sclerosis, following 20 years of mounting evidence showing a...

Blood sample for Epstein-Barr virus (EBV) test. (stock image) Credit: © jarun011 / Fotolia

Epstein-Barr virus may affect health in more ways than known. A far-reaching study conducted by scientists at Cincinnati Children’s reports that the Epstein-Barr virus (EBV) – best known for causing mononucleosis – also increases the risks for some people of developing seven other major diseases. Those diseases are: systemic lupus erythematosus (SLE), multiple sclerosis (MS), rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), inflammatory bowel disease (IBD), celiac disease, and type 1 diabetes. Combined, these seven diseases affect nearly 8 million people in the U.S.

Study results published April 12 in the journal Nature Genetics...

TFC cells express CXCR5 to localize to B cell follicles.

New research has taken us a step closer to finding a cure for HIV, as well as other infections including the glandular fever virus, which is associated with the development of lymphoma. Some infections, such as HIV, cannot be cured with antiviral therapy because the virus effectively hides from the immune system.

An international team of scientists have discovered that killer T cells can find these “hidden” infected cells in tissue and destroy them. “We’ve shown for the first time that there are specialised killer T cells that can migrate into a part of the lymphoid tissue and control hidden infection,” Dr Yu said.

Although treatments for HIV with antiretroviral drugs are highly effective, treatment is lifelong and there is no cure...