EEG tagged posts

Select Antieleptic drugs target mechanisms of epileptogenesis involving amyloid β and tau. Subclinical epileptiform activity in patients with Alzheimer’s disease can lead to accelerated cognitive decline and may be treated with AEDs like Levetiracetam.

Feasibility study suggests suppressing seizure-like activity may help patients. In the last decade, mounting evidence has linked seizure-like activity in the brain to some of the cognitive decline seen in patients with Alzheimer’s disease. Patients with Alzheimer’s disease have an increased risk of epilepsy and nearly half may experience subclinical epileptic activity – disrupted electrical activity in the brain that doesn’t result in a seizure but which can be measured by electroencephalogram (EEG) or other brain scan technology.

In a rece...

The amygdala of the human brain is placed somewhat strategically at dorsomedial part (above and inside) of temporal lobe, anteriorly (in front) of the hippocampus and close to the tail of the caudate nucleus.

Training the brain to treat itself is a promising therapy for traumatic stress. The training uses an auditory or visual signal that corresponds to the activity of a particular brain region, called neurofeedback, which can guide people to regulate their own brain activity. However, treating stress-related disorders requires accessing the amygdala that is difficult to reach with typical neurofeedback methods. This activity has only been measured using fMRI, which is costly and poorly accessible.

“The major advancement of this new tool is the ability to use a low-cost and accessible imag...

Canine electrode locations and data segments. (A) For the canine subjects, bilateral pairs of 4-contact strips were implanted oriented along the anterior-posterior direction. Electrode wires were tunnelled through the neck and connected to an implanted telemetry device secured beneath the latissimus dorsi muscle. (B) An hour of data with a 5-min offset before each lead seizure was extracted and split into 10-min segments for analysis. (C) The expanded view illustrates a ∼35-s long seizure.

It might sound like a riddle: What do you get when you combine 1 online contest, 2 patients, 5 five dogs and 654 data scientists? The answer: Hope for patients with epilepsy that their seizures can be reliably predicted, and perhaps prevented...

A computer in the lab of Miguel Nicolelis, M.D., Ph.D., monitors brain signals from a rhesus macaque. Nicolelis and Duke researchers record signals from hundreds of neurons in two regions of the monkeys’ brains that are involved in movement and sensation. As the animals think about moving toward their goal — in this case, a bowl containing fresh grapes — computers translate their brain activity into real-time operation of a wheelchair. Credit: Shawn Rocco/ Duke Health

Neuroscientists have developed a brain-machine interface (BMI) that allows primates to use only their thoughts to navigate a robotic wheelchair. The BMI uses signals from hundreds of neurons recorded simultaneously in 2 regions of the monkeys’ brains that are involved in movement and sensation...