EGFR cancer gene tagged posts

The discovery by Yale researchers may help lead to individualized treatments for lung cancer and other types of cancer. © blueringmedia – stock.adobe.com

A Yale-led study describes how EGFR cancer gene silences genes that typically suppress tumors. The finding may lead to the development of more effective, individualized treatment for patients with lung cancer and other cancer types. Mutations in the EGFR gene are linked to multiple cancer types, including cancers of the lung, brain, and breast. Yet scientists did not know precisely how EGFR represses genes that prevent cancers. The Yale team conducted multiple experiments and found that EGFR silences tumor suppressor genes in lung cancer and glioblastoma, a type of brain cancer.

“EGFR can target multiple unrelated tumor suppressor gene...