The images above show, from left to right, functioning stem cells, stem cells no longer functioning due to Hutchinson-Gilford Progeria syndrome (HGPS), and stem cells previously not functioning due to HGPS that were rebooted by the embryonic stem cell gene Nanog. Credit: Stelios Andreadis.
The discovery may lead to treatments for atherosclerosis, osteoporosis, Alzheimer’s and other age-related disorders. The fountain of youth may reside in an embryonic stem cell gene named Nanog. In a series of experiments at the University at Buffalo, the gene kicked into action dormant cellular processes that are key to preventing weak bones, clogged arteries and other telltale signs of growing old...
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