endocrine disruptor tagged posts

Micrograph showing a lymph node invaded by ductal breast carcinoma, with extension of the tumour beyond the lymph node. Credit: Nephron/Wikipedia

Bisphenol S, a substitute for bisphenol A (BPA) in the plastic industry, shows the potential for increasing the aggressiveness of breast cancer through its behavior as an endocrine-disrupting chemical, a new study finds. The results, which tested BPS in human breast cancer cells, will be presented Saturday at ENDO 2017, the Endocrine Society’s 99th annual meeting in Orlando, Fla.

BPS is found in polycarbonate hard plastics, currency bills and thermal paper receipts as well as many products touted to be free of BPA, a known endocrine-disrupting chemical suspected of having multiple possible health risks...

Far right, a zebrafish embryo breaks free from a group of unhatched sibling eggs. Credit: Zebrafish Lab

New UCLA research demonstrates that BPS (Bisphenol S), a common replacement for BPA, speeds up embryonic development and disrupts the reproductive system. The animal study is the first to examine the effects of BPA and BPS on key brain cells and genes that control the growth and function of organs involved in reproduction.

“Our study shows that making plastic products with BPA alternatives does not necessarily leave them safer,” explained senior author Nancy Wayne, a reproductive endocrinologist and a professor of physiology at the David Geffen School of Medicine at UCLA.

Using a zebrafish model, Wayne and her colleagues found that exposure to low levels of BPA and BPS — equivalent to th...