Neurons say relax: This three-dimensional view of part of a mouse intestine shows the neurons that surround tissue-protective immune cells. These neurons release norepinephrine, which instructs the immune cells to activate an anti-inflammatory response.
The immune system must protect against potential infections, but over-vigilant reactions can cause problems. New research shows neurons in the intestine send signals to immune cells to curb inflammation. This could have Rx implications for gastrointestinal diseases such as IBS.
Lamina propria macrophages are found very close to the lining of the intestinal tube, while muscularis macrophages are in a deeper tissue layer, more distant from what passes through the intestine...
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