exercise tagged posts

Exercise-induced ROS activates Nrf2, which then translocates into the nucleus to increase the expression of antioxidant enzymes. Antioxidant response element (ARE), carbon monoxide (CO), Glutathione peroxidase (GPx), Glutathione S-transferase (GST), Heme oxygenase-1 (HO-1), Kelch-like ECH-associated protein 1 (Keap1), NAD(P)H quinone oxidoreductase-1 (NQO-1), and nuclear factor erythroid 2-related factor 2 (Nrf2).

If you’re an older adult, a 30 min workout may not be as effective, even at the cellular level, as it was when you were younger. According to a new study, age may play a significant role in a cell’s ability to respond to that activity. In the study, a group of men 18 to 30 yo were tested against a group of older men 55 years and older...

“These are individuals in their 80s and 90s who actively compete in world masters track and field championships. We have seven world champions. These individuals are the crème de la crème of aging.”

A Uni of Guelph professor has uncovered the “secret” to staying strong as we age – superb fitness. Geoff Power found elderly people who were elite athletes in their youth or later in life – and who still compete as masters athletes – have much healthier muscles at the cellular level compared to those of non-athletes.

The study compared world-class track and field athletes in their 80s with people of the same age who are living independently. There have been few such studies of aging and muscle weakening in masters athletes in this age group...

Exercise, alone or in combination with education, may reduce the risk of low back pain, a meta-analysis and review of medical literature suggests. Daniel Steffens, Ph.D., of the University of Sydney, Australia, and coauthors identified 23 published reports (on 21 different randomized clinical trials including 30,850 participants) that met their inclusion criteria.

Moderate-quality evidence suggests exercise combined with education reduces the risk of an episode of low back pain and low- to very low-quality evidence suggests exercise alone may reduce the risk of both a low back pain episode and the use of sick leave. Other interventions, including education alone, back belts and shoe inserts do not appear to be associated with the prevention of low back pain.

“Although our review found evi...

Microbes under a microscope. Credit: NIAID

The research indicates that there may be a window of opportunity during early human development to optimize the chances of better lifelong health.
“Exercise affects many aspects of health, both metabolic and mental, and people are only now starting to look at the plasticity of these gut microbes,” said Prof Monika Fleshner. Microbes take up residence within human intestines shortly after birth and are vital to the development of the immune system and various neural functions. These microbes can add as many 5 million genes to a person’s overall genetic profile and thus have tremendous power to influence aspects of human physiology.

While this diverse microbial community remains somewhat malleable throughout adult life and can be influenced by envir...