Clearance of senescent cells prolongs healthspan
Researchers have shown senescent cells – cells that no longer divide and accumulate with age – negatively impact health and shorten lifespan by as much as 35% in normal mice. The results demonstrate that clearance of senescent cells delays tumor formation, preserves tissue and organ function, and extends lifespan without observed adverse effects.
“Cellular senescence is a biological mechanism that functions as an ’emergency brake’ used by damaged cells to stop dividing,” says Jan van Deursen, Ph.D., Chair of Biochemistry and Molecular biology at Mayo Clinic...
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