FAP expression tagged posts

Blocking Enzyme in Normal cells may impede Pancreatic cancer, team shows

Puré FAP expression

Researchers showed that FAP (middle panels) is overexpressed in pancreatic tumors compared to normal pancreatic tissue. Particularly high levels of FAP expression were associated with poorer outcomes. Credit: University of Pennsylvania

New findings from a University of Pennsylvania-led team offer a promising target for future therapies that could potentially root out even well-hidden metatstatic cancer lesions. When they deleted the gene encoding this protein in mice with the disease, the animals lived longer, and the cancer’s spread to other organs was reduced...

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