Scientists at Johns Hopkins Medicine using MRI scans and computer modeling say they have further pinpointed areas of the human brain that regulate efforts to deal with fatigue.
The findings, they say, could advance the development of behavioral and other strategies that increase physical performance in healthy people, and also illuminate the neural mechanisms that contribute to fatigue in people with depression, multiple sclerosis and stroke.
Results of the research were published online Aug. 12 in Nature Communications.
“We know the physiologic processes involved in fatigue, such as lactic acid build-up in muscles, but we know far less about how feelings of fatigue are processed in the brain and how our brain decides how much and what kind of effort to make t...
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