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Fighting Tumours with Magnetic Bacteria

Illustration of a blood vessel as well as the blood cells and the magnetic bacteria
Magnetic bacteria (grey) can squeeze through narrow intercellular spaces to cross the blood vessel wall and infiltrate tumours. (Visualisations: Yimo Yan / ETH Zurich)

Researchers at ETH Zurich are planning to use magnetic bacteria to fight cancerous tumours. They have now found a way for these microorganisms to effectively cross blood vessel walls and subsequently colonise a tumour.

Scientists around the world are researching how anti-cancer drugs can most efficiently reach the tumours they target. One possibility is to use modified bacteria as “ferries” to carry the drugs through the bloodstream to the tumours. Researchers at ETH Zurich have now succeeded in controlling certain bacteria so that they can effectively cross the blood vessel wall and infiltrate tumour tissue.

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