FLP-7 tagged posts

FLP-7 and NPR-22 function as a fat regulatory neuroendocrine ligand-receptor pair in vivo.

Biologists at TSRI have identified a brain hormone that appears to trigger fat burning in the gut. Their findings in animal models could have implications for future pharmaceutical development. “This was basic science that unlocked an interesting mystery,” said TSRI Assistant Professor Supriya Srinivasan. Previous studies had shown that serotonin can drive fat loss. Yet no one was sure exactly how.

To answer that question, Srinivasan and her colleagues experimented with C. elegans, which are often used as model organisms in biology...