follicular cytotoxic T cells tagged posts

Big step towards Cure for HIV and other Lifelong Viral Infections

TFC cells express CXCR5 to localize to B cell follicles.

TFC cells express CXCR5 to localize to B cell follicles.

New research has taken us a step closer to finding a cure for HIV, as well as other infections including the glandular fever virus, which is associated with the development of lymphoma. Some infections, such as HIV, cannot be cured with antiviral therapy because the virus effectively hides from the immune system.

An international team of scientists have discovered that killer T cells can find these “hidden” infected cells in tissue and destroy them. “We’ve shown for the first time that there are specialised killer T cells that can migrate into a part of the lymphoid tissue and control hidden infection,” Dr Yu said.

Although treatments for HIV with antiretroviral drugs are highly effective, treatment is lifelong and there is no cure...

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