food allergies tagged posts

Highlights •Dietary fiber with vitamin A increases the potency of tolerogenic CD103+ DCs •High-fiber diet protects mice against peanut allergy via gut microbiota and SCFA •High-fiber effects rely on epithelial GPR43 and immune cell GPR109a •Dietary fiber promotes TFH and IgA responses

The development of food allergies in mice can be linked to what their gut bacteria are being fed. Rodents that received a diet with average calories, sugar, and fiber content from birth were shown to have more severe peanut allergies than those that received a high-fiber diet. The researchers show that gut bacteria release a specific fatty acid in response to fiber intake, which eventually impacts allergic responses via changes to the immune system.

“We felt that the increased incidence of food allerg...