GABA tagged posts

The neuroactive potential of bacteria living in the human gut is associated with levels of key chemicals in the brain, according to a new study published in Molecular Psychiatry. The research team from the University of Surrey and the University of Roehampton found that microbial pathways involved in producing and breaking down neuroactive compounds were associated with levels of GABA and glutamate in specific regions of the human brain.

GABA and glutamate are two of the brain’s most important chemical messengers. GABA predominantly dampens neural activity, while glutamate promotes excitation...

The origin of neurodegenerative diseases like Alzheimer’s or dementia isn’t limited to the brain. The state of your gut can quietly set off a cycle of chronic, system-wide inflammation that nudges the brain toward cognitive decline. But how does the pathogenesis of a disease that seems purely brain-based begin in the gut—an organ that is mostly busy producing chemicals for digesting food?

It turns out these two entities are linked by the gut-brain axis, a two-way communication superhighway that constantly sends signals between the digestive tract and the central nervous s...

One of the largest threats to human health is obesity, but now researchers from the University of Aberdeen Rowett Institute have made an important discovery in how the brain controls food intake.

Obesity and being overweight have become the “new normal” in modern times and can lead to a multitude of health problems. We know that excess weight is primarily caused by eating more calories than the body needs; however, new research published in Current Biology has found a specific cluster of cells in the brain that control body weight.

How the brain controls hunger has not been fully defined. The researchers discovered a cluster of brain cells that can be harnessed to reduce food intake and body weight...