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    Gastric Cancer tagged posts

    Simple ‘Swish-and-Spit’ Oral Rinse could provide Early Screening for Gastric Cancer

    May 10, 2024, Categories  Biology/Biotechnology, Health/Medical

    oral rinse
    Credit: Unsplash/CC0 Public Domain

    A simple oral rinse could provide early detection of gastric cancer, the fourth-leading cause of cancer deaths worldwide, according to a study scheduled for presentation at Digestive Disease Week (DDW) 2024.

    “In the cancer world, if you find patients after they’ve developed cancer, it’s a little too late,” said Shruthi Reddy Perati, MD, author and general surgery resident at Rutgers Robert Wood Johnson School of Medicine. “The ideal time to try to prevent cancer is when it’s just about to turn into cancer. We were able to identify people who had precancerous conditions. As a screening and prevention tool, this has enormous potential.”

    Researchers analyzed bacteria samples from the mouths of 98 patients scheduled for endoscopy, including 30 known...

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    How Inflammation causes Gastric Cancer

    April 17, 2019, Categories  Biology/Biotechnology, Health/Medical

    A schematic illustration of the role of Noxo1 and NOX1 in the inflammation-associated gastric tumorigenesis. Helicobacter pylori infection causes chronic gastritis, which further induces expression of Noxo1 through TNF-α/NF-κB inflammatory cytokine pathway. Induction of Noxo1 as well as other NOX1 complex, such as NOX1, Noxa1 and Cyba, leads to activation of NOX1 complex and ROS production. Increased ROS level in the inflamed gastric mucosa results in expansion of SOX2-positive stem cell population, which induces gastritis-associated gastric metaplasia and hyperplasia. This Noxo1-involved inflammatory pathway contributes to gastric tumorigenesis in the H. pylori-infected stomach.
    CREDIT
    Kanazawa University

    Researchers have solved the decades-old mystery of how stomach bacterium He...

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