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A groundbreaking nanosurgical tool — about 500 times thinner than a human hair — could be transformative for cancer research and give insights into treatment resistance that no other technology has been able to do, according to a new study.

The high-tech double-barrel nanopipette, developed by University of Leeds scientists, and applied to the global medical challenge of cancer, has — for the first time — enabled researchers to see how individual living cancer cells react to treatment and change over time — providing vital understanding that could help doctors develop more effective cancer medication.

The tool has two nanoscopic needles, meaning it can simultaneously inject and extract a sample from the same cell, expanding its potential uses...

Vibrant green leaves sprout from tall fragrant plants sitting neatly in two rows of terracotta pots in Valerie Sponsel’s UTSA biology laboratory. One floor just above her is the chemistry lab of Francis Yoshimoto, who is extracting the plant’s leaves for medicinal compounds. Soon, the researchers will meet with UTSA researcher Annie Lin, who will test the extracted compounds on cancer cells.

The plant is Artemisia annua, or Sweet Annie, and it contains medicinal compounds. UTSA researchers are studying the plant to understand the bioactive properties of one of these compounds, Arteannuin B, in cancer cells and COVID, the disease caused by the virus, SARS-CoV-2.

“Around 50% of prescription drugs are derived from natural products. They’re made by plants, fungi or bacteria...

The University of Alabama in Huntsville (UAH) has announced that three researchers associated with the UAH Center for Space Plasma and Aeronomic Research (CSPAR) have discovered a gamma-ray burst (GRB) approximately 2...

PFF limits spread of glioblastoma multiforme, or GBM – the most common primary tumor of the brain and CNS by targeting protein TROY. In addition, TGen lab research also found PPF increases effectiveness of a standard-of-care chemotherapy drug called temozolomide (TMZ), and radiation, to treat glioblastoma. “We showed that PPF decreased glioblastoma cell expression of TROY, inhibited glioma cell invasion, and made brain cancer cells more vulnerable to TMZ and radiation,” said Dr. Nhan Tran, Ass Prof and head of TGen’s Central Nervous System Tumor Research Lab.

An advantage of small-molecule PPF – previously used in clinical trials in an attempt to treat Alzheimer’s disease and dementia – is that it can penetrate the blood-brain barrier and reach the tumor...