gene promoters tagged posts

Workers representing the repair system known as nucleotide excision repair (NER), repairing DNA and snakes, representing proteins that bind DNA at gene promoters, potentially preventing them from doing this. Credit: Jackie Mostek

DNA repair is compromised at important regions of our genome, shedding new light on the human body’s capacity to repair DNA damage, UNSW medical scientists have discovered. Repairing damage in DNA from anything that causes a mutation, such as UV radiation and tobacco smoke, is a fundamental process that protects our cells from becoming cancerous.

The scientists analysed > 20 million DNA mutations from 1,161 tumours across 14 cancer types...