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    gene signature tagged posts

    Gene Signature predicts whether Localized Prostate Cancer is likely to Spread

    November 12, 2020, Categories  Biology/Biotechnology, Health/Medical

    META-16 is correlated with MYC and RAS pathway activation and enriched in prostate cancer metastasis.

    Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease. The new gene signature may also be useful for evaluating responses to treatment and for developing new therapies to prevent or treat advanced prostate cancer.

    “If we could know in advance which patients will develop metastases, we could start treatments earlier and treat the cancer more aggressively,” says the study’s senior author, Cory Abate-Shen, PhD, chair of the Department of Molecular Pharmacology and Therapeutic...

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    Early Warning RNA Signature for Alzheimer’s

    September 7, 2015, Categories  Biology/Biotechnology, Health/Medical

    The healthy ageing RNA signature in healthy human brain tissue and blood of AD patients and controls. There was robust regulation of the healthy ageing RNA signature in human brain with healthy ageing and between control subjects and subjects with AD or MCI.

    The healthy ageing RNA signature in healthy human brain tissue and blood of AD patients and controls. There was robust regulation of the healthy ageing RNA signature in human brain with healthy ageing and between control subjects and subjects with AD or MCI.

    The healthy ageing RNA signature in healthy human brain tissue and blood of AD patients and controls. There was robust regulation of the healthy ageing RNA signature in human brain with healthy ageing and between control subjects and subjects with AD or MCI. a The healthy ageing RNA signature was studied across brain regions in healthy individuals using BrainEac.org gene-chip resource [GEO:GSE60862]...
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