The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal Neurons
A new study shows the death of newborn brain cells may be linked to a genetic risk factor for schizophrenia, bipolar disorder, autism, ADHD, and depression, and at the same time shows a compound currently being developed for use in humans may have therapeutic value for these diseases by preventing the cells from dying.
In 2013, the largest genetic study of psychiatric illness to date implicated mutations in the gene called CACNA1C as a risk factor in 5 major forms of neuropsychiatric disease. All the conditions also share the common clinical feature of high anxiety...
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