GERD tagged posts

A Comparison of Alkaline Water and Mediterranean Diet vs Proton Pump Inhibition for Treatment of Laryngopharyngeal Reflux. JAMA Otolaryngology–Head & Neck Surgery, 2017; DOI: 10.1001/jamaoto.2017.1454

A plant-based, Mediterranean-style diet has been shown to provide the same medical benefits for treating laryngopharyngeal reflux as popular reflux medications. This is according to a study published in JAMA Otolaryngology Head Neck Surgery by researchers from Northwell Health’s The Feinstein Institute for Medical Research and New York Medical College.

When compared to patients who took the traditional reflux medication, proton pump inhibitors (PPI), those patients who consumed a 90-95% whole food, plant-based, Mediterranean-style diet paired with alkaline water had the same if not better r...

MLCK and RLC phosphorylation are required for the basal tone in IAS.

A new molecular pathway critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system. This finding, based on studying calcium ion-controlled pathways in mice, may lead to new treatments for a host of digestive disorders ranging from common gastroesophageal reflux disease (GERD), to swallowing disorders, incontinence and pancreatitis.

A/Prof Ronghua ZhuGe, PhD said:. “Knowing how these muscles stay contracted for such long periods of time will allow us to develop potential new treatments for these diseases. The next step is to see whether this molecular mechanism in mice also operates in humans...