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High-Fat Diet Starves the Brain

Cross-section through the brain of a mouse: regions with reduced uptake of glucose after three days of a high-fat diet (blue: slightly reduced, white: greatly reduced). [less] © MPI f. Metabolism Research

Cross-section through the brain of a mouse: regions with reduced uptake of glucose after three days of a high-fat diet (blue: slightly reduced, white: greatly reduced). © MPI f. Metabolism Research

A high-fat diet of 3 days in mice leads to a reduction in the amount of glucose that reaches the brain. The mouse brain restored its sugar uptake after 4 weeks, albeit at the cost of the rest of the body. High-fat-content foods throw our bodies out of kilter. Obesity and diseases such as type 2 diabetes can be the result. But what does a high-fat diet actually do to our brain? Scientists from the Max Planck Institute for Metabolism Research in Cologne have looked into the brains of mice to understand how obesity and diabetes develop.

“A high-fat diet reduces the uptake of blood glucose into the ...

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