glycine tagged posts

GlyNAC Improves Multiple Defects in Aging to Boost Strength and Cognition in Older Humans

African-American men needed for prostate cancer study

A pilot human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC — a combination of glycine and N-acetylcysteine as precursors of the natural antioxidant glutathione — could improve many age-associated defects in older humans to improve muscle strength and cognition, and promote healthy aging.

Published in the journal Clinical and Translational Medicine, the results of this study show that older humans taking GlyNAC for 24 weeks saw improvements in many characteristic defects of aging, including glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, body fat, genomic toxicity, muscle strength, gait speed, exercise capacity and cognitive function...

Read More

Molecular Evolution: How the Building Blocks of Life may Form in Space

Star forming region (Pillars of Creation) in the Eagle Nebula. Low-energy electrons, created in matter by space radiation (e.g., galactic cosmic rays, GCR, etc.), can induce formation of glycine (2HN-CH2-COOH) in astrophysical molecular ices; here, icy grains of interstellar dust (or ices on planetary satellites) are simulated by ammonia, methane and carbon dioxide condensed at 20 K on Pt in UHV, and irradiated by 0-70 eV LEEs. Credit: NASA, Hubble, STScI

Star forming region (Pillars of Creation) in the Eagle Nebula. Low-energy electrons, created in matter by space radiation (e.g., galactic cosmic rays, GCR, etc.), can induce formation of glycine (2HN-CH2-COOH) in astrophysical molecular ices; here, icy grains of interstellar dust (or ices on planetary satellites) are simulated by ammonia, methane and carbon dioxide condensed at 20 K on Pt in UHV, and irradiated by 0-70 eV LEEs. Credit: NASA, Hubble, STScI

New research offers evidence that humans – and the rest of life on Earth – may have been able to form with the right combination of star dust and radiation...

Read More

Amino Acids in Diet could be key to Starving Cancer

The serine synthesis pathway.

Serine and glycine can be taken up by cells through neutral amino acid transporters or synthesized de novo.

Cutting out certain amino acids from the diet of mice slows tumor growth and prolongs survival, according to new research published in Nature. Researchers at the Cancer Research UK Beatson Institute and the University of Glasgow found that removing 2 non-essential amino acids – serine and glycine – from the diet of mice slowed the development of lymphoma and intestinal cancer. The researchers also found that the special diet made some cancer cells more susceptible to chemicals in cells called reactive oxygen species.

Chemotherapy and radiotherapy boost levels of these chemicals in the cells, so this research suggests a specially formulated diet could make conventional cancer treatmen...

Read More

Rosetta’s Comet contains Ingredients for Life

Rosetta's comet in August 2015, when it was closest to the sun and when most of the glycine was detected. Credit: ESA

Rosetta’s comet in August 2015, when it was closest to the sun and when most of the glycine was detected. Credit: ESA

Ingredients crucial for the origin of life on Earth, including the simple amino acid glycine and phosphorus, key components of DNA and cell membranes, have been discovered at Comet 67P/Churyumov-Gerasimenko. The possibility that water and organic molecules were brought to the early Earth through impacts of objects like asteroids and comets have long been the subject of important debate...

Read More