Anti-inflammatory nanoparticles mimic glycocalyx. Chronic inflammatory bowel disease (IBD), such as Crohn’s disease and ulcerative colitis, is on the rise worldwide. The benefits of current medications are limited by problematic side effects. In the journal Angewandte Chemie, a South Korean research team has now introduced a new method of treatment. It is based on nanoparticles that mimic a special carbohydrate layer (glycocalyx) located on inflamed bowel cells, and which trigger anti-inflammatory effects in the diseased sites in the intestine.
Stomach cramps and severe diarrhea, often accompanied by significant weight loss, are some o...
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