New findings in Nature reveal how age-related gut changes fuel the growth of pre-leukemic blood cells. Scientists at Cincinnati Children’s along with an international team of researchers have discovered a surprising new connection between gut health and blood cancer risk — one that could transform how we think about aging, inflammation, and the early stages of leukemia.
As we grow older — or in some cases, when gut health is compromised by disease — changes in the intestinal lining allow certain bacteria to leak their byproducts into the bloodstream. One such molecule, produced by specific bacteria, acts as a signal that accelerates the expansion of dormant, pre-leukemic blood cells, a critical step to developing full-blown leukemia.
The team’s findings — published April 23, 202...
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