Gut bacteria tagged posts

Gut bacteria and acetate team up to cut fat in mice without muscle loss

Gut bacteria and acetate, a great combination for weight loss
Credit: Cell Metabolism (2025). DOI: 10.1016/j.cmet.2025.04.013

Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered a new way to reduce obesity. Their study shows that supplying the gut with extra acetate reduces fat and liver mass in both normal and obese mice, as long as bacteria of the Bacteroides species are also present in the gut.

When both these conditions are met, gut bacteria can eliminate more sugars from the gut and promote the burning of fats for energy in the host. The findings were published in Cell Metabolism.

Affecting hundreds of millions of people around the world, obesity constitutes a global epidemic...

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Protein in Soy may Reduce the Risk of Heart Failure by Affecting Gut Bacteria

A research team from the Nagoya University Graduate School of Medicine has discovered a promising way to slow the progression of heart failure in mice. They fed mice a diet rich in the soybean protein, β-conglycinin (β-CG), which can support heart health by influencing gut bacteria. Their analysis revealed that the soybean protein rich diet increased the production of the short-chain fatty acids (SCFAs) in the intestine that play a role in protecting the heart. Their findings were published in Clinical Nutrition.

Many people with heart problems try to eat a nutritious diet to reduce their risk of disease. As part of a healthy diet, soybeans have long been recognized for their antioxidant and anti-inflammatory properties...

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Dietary Fiber found to Regulate Gut Bacteria’s use of Tryptophan, Impacting Health

Dietary fibers make our gut bacteria behave healthy
The essential amino acid tryptophan is converted in the large intestine into either beneficial or harmful substances. The research shows that tryptophan contributes to the production of the healthy substances Indole lactic acid (ILA) and Indole propionic acid (IPA) when we consume sufficient amounts of dietary fiber. However, if we do not get enough dietary fiber, tryptophan will be converted into the substance indole, which is associated with adverse health effects. The figure is created with BioRender (biorender.com) by Martin Frederik Laursen. Credit: The figure is created with BioRender (biorender.com) by Martin Frederik Laursen.

We get healthy dietary fiber from consuming fruits, vegetables, and whole grains...

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Gut Bacteria affect Brain Health, Mouse study shows

Gut bacteria can influence brain health, according to a study of mice genetically predisposed to develop Alzheimer’s-like brain damage. The study, by researchers at Washington University School of Medicine in St. Louis, indicates that gut bacteria produce compounds that influence the behavior of immune cells, including ones in the brain that can cause neurodegeneration. The findings suggest a new approach to treating Alzheimer’s and other neurodegenerative diseases. Getty Images

Findings suggest new approach to treating Alzheimer’s, other neurodegenerative diseases. Gut bacteria can influence brain health, according to a study of mice genetically predisposed to develop Alzheimer’s-like brain damage...

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