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Brain-to-Gut Connections traced

Neuroscientists at the University of Pittsburgh Brain Institute have traced neural pathways that connect the brain to the stomach, providing a biological mechanism to explain how stress can foster ulcer development.

The findings, published this week in the Proceedings of the National Academy of Sciences, build a scientific basis for the brain’s influence over organ function and emphasize the importance of the brain-body connection.

Until now, research exploring the gut-brain interaction has largely focused on the influence of the gut and its microbiome on the brain. But it’s not a one-way street – the brain also influences stomach function.

“Pavlov demonstrated many years ago that the central nervous system uses environmental signals and past experience to generate anti...

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