Gut Microbes tagged posts

Your gut microbes can be anti-aging—scientists are uncovering how to keep your microbiome youthful

People have long given up on the search for the Fountain of Youth, a mythical spring that could reverse aging. But for some scientists, the hunt has not ended—it’s just moved to a different place. These modern-day Ponce de Leóns are investigating whether gut microbes hold the secret to aging well.

The gut microbiome refers to the vast collection of microscopic organisms—bacteria, fungi, and viruses—that largely inhabit the colon. These microbes aid in digestion and produce molecules that affect your physiology and psychology. The composition of the microbiome is influenced by a combination of factors, including genetics, diet, the environment, medications, and age.

I’m a microbiology professor and author of “Pleased to Meet Me: Genes, Germs and the Curious Forces That Mak...

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Newly discovered ‘sixth sense’ links gut microbes to the brain in real time

Sixth Sense' Links Gut Microbes to the Brain in Real Time - ScienceBlog.com

In a breakthrough that reimagines the way the gut and brain communicate, researchers have uncovered what they call a “neurobiotic sense,” a newly identified system that lets the brain respond in real time to signals from microbes living in our gut.

The new research, led by Duke University School of Medicine neuroscientists Diego Bohórquez, Ph.D., and M. Maya Kaelberer, Ph.D., published in Nature, centers on neuropods, tiny sensor cells lining the colon’s epithelium. These cells detect a common microbial protein and send rapid messages to the brain that help curb appetite.

But this is just the beginning...

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Gut microbes release cancer-fighting bile acids that block hormone signals

Gut microbes release cancer-fighting bile acids that block hormone signals
Graphical abstract. Credit: Cell (2025). DOI: 10.1016/j.cell.2025.02.029

Bacteria naturally present in the human intestine (known as the gut microbiota) can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study led by Weill Cornell Medicine investigators. The study was published on April 15 in Cell.

“I was very surprised by our findings. As far as I know, no one has previously discovered molecules like these bile acids that can interact with the androgen receptor in this way,” said co-senior author Dr...

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An Avocado a day keeps your Gut Microbes Happy, study shows

Adding avocado to your meal improves gut health, a new University of Illinois study shows.

Eating avocado as part of your daily diet can help improve gut health, a new study from University of Illinois shows. Avocados are a healthy food that is high in dietary fiber and monounsaturated fat. However, it was not clear how avocados impact the microbes in the gastrointestinal system or “gut.”

“We know eating avocados helps you feel full and reduces blood cholesterol concentration, but we did not know how it influences the gut microbes, and the metabolites the microbes produce,” says Sharon Thompson, graduate student in the Division of Nutritional Sciences at U of I and lead author on the paper, published in the Journal of Nutrition.

The researchers found that people who ate avocado e...

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