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The IL-17 Protein plays a Key Role in Skin Aging

Immunofluorescence staining of IL-17(white) in aged mouse skin

A team of scientists from the Institute for Research in Biomedicine (IRB Barcelona) in collaboration with the National Center for Genomic Analysis (CNAG) has discovered that IL-17 protein plays a central role in skin ageing. The study, which was led by Dr. Guiomar Solanas, Dr. Salvador Aznar Benitah, both at IRB Barcelona, and Dr. Holger Heyn, at CNAG, highlights an IL-17-mediated ageing process to an Inflammatory state.

Skin ageing is characterised by a series of structural and functional changes that gradually contribute to the deterioration and fragility associated with age. Aged skin has a reduced capacity to regenerate, poor healing ability, and diminished barrier function.

Published in the journal Nature Aging, ...

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