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    Team develops Fluid Biomarker for Early Detection of Amyotrophic Lateral Sclerosis, ALS and Frontotemporal Dementia

    March 19, 2024, Categories  Biology/Biotechnology, Health/Medical

    Johns Hopkins Medicine-led team develops fluid biomarker for early detection of ALS and FTD
    A Johns Hopkins Medicine-led team has developed a fluid biomarker that may one day detect two degenerative diseases, ALS and FTD, before symptoms appear. The biomarker locates a protein associated with the loss of function for the TDP-43 protein (seen as a molecular model in this image), an abnormality linked to people who develop ALS or FTD. Credit: Public domain image via Protopedia.org

    Two progressively degenerative diseases, amyotrophic lateral sclerosis (ALS, commonly known as Lou Gehrig’s disease) and frontotemporal dementia (FTD, recently in the news with the diagnoses of actor Bruce Willis and talk show host Wendy Williams), are linked by more than the fact that they both damage nerve cells critical to normal functioning—the former affecting nerves in the brain and spinal cord ...

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