heart attack tagged posts

Marijuana use associated with Increased Risk of Stroke, Heart Failure

As marijuana legalization spreads, better understanding of side effects is needed. Using marijuana raises stroke and heart failure risk even after accounting for demographic factors, other health conditions and lifestyle risk factors such as smoking and alcohol use, according to research scheduled for presentation at the American College of Cardiology’s 66th Annual Scientific Session. While previous marijuana research has focused mostly on pulmonary and psychiatric complications, the new study is one of only a handful to investigate cardiovascular outcomes.

The study drew data from the Nationwide Inpatient Sample, which includes the health records of patients admitted at more than 1,000 hospitals comprising about 20% of U.S. medical centers...

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Lowering Cholesterol to ‘levels of a New-born’ cuts Heart Attack Risk

Lowering cholesterol to 'levels of a new-born' cuts heart attack risk

Reductions in Atherogenic Lipids and Major Cardiovascular Events A Pooled Analysis of 10 ODYSSEY Trials Comparing Alirocumab With Control Credit: Imperial College London

Although previous studies have suggested lowering cholesterol levels may be associated with a lower risk of heart attack, recent evidence has questioned whether very low levels are beneficial.
In the latest study, led by scientists at Imperial College London, researchers analysed data from over 5,000 people taking part in cholesterol-lowering trials. These studies utilised a new therapy to reduce cholesterol to much lower levels than previously possible.

The scientists found that dropping cholesterol to the lowest level possible – to levels similar to those we were born with – reduced the risk of heart attack, stroke or fa...

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Omega-3 Fatty Acids from fish oil, may aid Healing after Heart Attack

Heart illustration with artery close up

Heart illustration with artery close up Heart graphic with magnifier on artery copyright American Heart Association

Giving heart attack patients a high dose of omega-3 fatty acids from fish oil, daily for 6 months after a heart attack improved the function of the heart and reduced scarring in the undamaged muscle, according to new research in the American Heart Association’s journal Circulation. The heart’s shape and function can be altered after a heart attack, a condition known as post-heart attack remodeling and it is linked with poor patient outcomes and could lead to heart failure. Therapies that can improve healing of the heart or prevent adverse remodeling, remain scarce.

A previous study found that omega-3 fatty acids from fish oil were associated with improved survival for heart a...

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Gut Microbes influence Platelet function, risk of Thrombosis

Highlights •Elevated TMAO levels predict incident risk for thrombotic events in human subjects •TMAO enhances sub-maximal stimulus-dependent platelet activation •Dietary choline, gut microbes, and TMAO are linked to thrombotic potential in vivo •Microbial transplantation shows that thrombosis potential is a transmissible trait

Highlights •Elevated TMAO levels predict incident risk for thrombotic events in human subjects •TMAO enhances sub-maximal stimulus-dependent platelet activation •Dietary choline, gut microbes, and TMAO are linked to thrombotic potential in vivo •Microbial transplantation shows that thrombosis potential is a transmissible trait

TMAO – gut byproduct of animal-rich diets – encourages over-reactive platelet function, increasing thrombosis risk. In a combination of both clinical studies of over 4,000 patients and animal model studies, Cleveland Clinic researchers have demonstrated – for the first time – that gut microbes alter platelet function and risk of blood clot-related illnesses like heart attack and stroke.

When the nutrient choline –which is abundant in animal products like meat...

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