heart disease tagged posts

Norbert Leitinger, Ph.D. (left), and Vlad Serbulea, Ph.D., of the University of Virginia School of Medicine, have determined why obesity causes harmful inflammation that can lead to diabetes, clogged arteries and other health problems. Doctors may be able to use this knowledge to battle these chronic diseases and others driven by damaging inflammation.
Credit: Dan Addison, University of Virginia Communications

Finding points to new approaches to battling diabetes, other chronic conditions. New research from the University of Virginia School of Medicine explains why obesity causes harmful inflammation that can lead to diabetes, clogged arteries and other health problems. Doctors may be able to use this knowledge to battle these chronic diseases and others driven by damaging inflammation...

Shown are cross-sectional ultrasound images of coronary arteries from patients enrolled in the study. Plaque buildup (colored areas) in an artery from a patient that lacks sensitivity to red meat allergen (left) is much lower than plaque levels in an artery from a patient with sensitivity to red meat allergen (right). Credit: Courtesy of Angela Taylor, M.D., University of Virginia Health System

A team of researchers says it has linked sensitivity to an allergen in red meat to the buildup of plaque in the arteries of the heart. While high saturated fat levels in red meat have long been known to contribute to heart disease for people in general, the new finding suggests that a subgroup of the population may be at heightened risk for a different reason – a food allergen...

UCLA researchers Tamer Sallam, left, and Peter Tontonoz expect that further exploration will lead to new insights into normal physiology as well as disease.

So-called ‘selfish’ gene acts to remove cholesterol from blood vessels. Scientists have identified a gene that may play a protective role in preventing heart disease. Their research revealed that the gene, called MeXis, acts within key cells inside clogged arteries to help remove excess cholesterol from blood vessels. Published in the journal Nature Medicine, the UCLA-led study in mice found that MeXis controls the expression of a protein that pumps cholesterol out of cells in the artery wall.

MeXis is an example of a “selfish” gene, one that is presumed to have no function because it does not make a protein product...

The degree of hair graying in male gender as an independent risk factor for coronary artery disease, a prospective study

Grey hair has been linked with an increased risk of heart disease in men, in research presented today at EuroPrevent 2017. “Ageing is an unavoidable coronary risk factor and is associated with dermatological signs that could signal increased risk,” said Dr Irini Samuel, a cardiologist at Cairo University, Egypt. Atherosclerosis and hair greying share similar mechanisms such as impaired DNA repair, oxidative stress, inflammation, hormonal changes and senescence of functional cells. This study assessed the prevalence of grey hair in patients with coronary artery disease and whether it was an independent risk marker of disease.

This was a prospective, observational study wh...