heart failure tagged posts

Gut Microbial Pathway identified as Target for Improved Heart Disease Treatment

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Topological designation of the secondary structure of β2AR. The figure displays the overlap of the secondary structures of the 4 crystal structures of β2AR used in this study.

Cleveland Clinic researchers have made a significant discovery about how the gut microbiome interacts with cells to cause cardiovascular disease. The study published in Nature Communications found that phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.

PAG was shown to interact with beta-2 adrenergic receptors to influence how forcefully the heart muscle cells contract—a process that investigators believe contributes to he...

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Study finds COVID-19 Vaccine can help people with Heart Failure Live Longer

COVID-19 vaccine
Credit: Pixabay/CC0 Public Domain

Heart failure patients who are vaccinated against COVID-19 have an 82% greater likelihood of living longer than those who are not vaccinated, according to research presented at Heart Failure 2024, a scientific congress of the European Society of Cardiology (ESC), held 11–14 May in Lisbon, Portugal. Heart Failure is a life-threatening syndrome affecting more than 64 million people worldwide.

“Patients with heart failure should be vaccinated against COVID-19 to protect their health,” said study author Dr. Kyeong-Hyeon Chun of the National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea.

“In this large study of patients with heart failure, COVID-19 vaccination was associated with a lower likelihood of contracting the infection, ...

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Researchers developed new method for Detecting Heart Failure with a Smartphone

The new technology, which was created at the University of Turku and developed by the company CardioSignal, uses a smartphone to analyse heart movement and detect heart failure. The study involved five organisations from Finland and the United States.

Heart failure is a condition affecting tens of millions of people worldwide, in which the heart is unable to perform its normal function of pumping blood to the body.

It is a serious condition that develops as a result of a number of cardiovascular diseases and its symptoms may require repeated hospitalisation.

Heart failure is challenging to diagnose because its symptoms, such as shortness of breath, abnormal fatigue on exertion, and swelling, can be caused by a number of conditions.

There is no simple test available to dete...

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Scientists Characterize the Imbalanced Gut Bacteria of Patients with Myocardial Infarction, Angina and Heart Failure

In two publications in Nature Medicine, a European-Israeli team of researchers show how major disturbances occur in the gut microbiome of patients suffering from heart disease. Given this latest evidence from microbiome research, one of the senior lead researchers, Professor Oluf Pedersen from the University of Copenhagen, calls for stronger and more focused public health initiatives to prevent or delay these common diseases that are a leading cause of premature death worldwide through plant-based and energy-controlled diet, avoidance of smoking and compliance with daily exercise.

The human gut contains trillions of bacteria, collectively called the gut microbiome, which may have positive and negative effects on human health...

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