
The human lymphatic system © Inserm, Léa Lemierre
In a new heart failure study, the blood system is being explored for the purpose of improving heart function. The study has revealed the potential of a secondary system that had previously received scant attention.
The researchers analysed the heart lymphatic system in an animal model which was highly impaired following a myocardial infarction. Using a biotherapy based on the injection of innovative microparticles, they succeeded in regenerating lymphatic vessels in a targeted manner. This treatment promotes lymphatic drainage, thus limiting post-infarct oedema and inflammation. Heart function is thereby improved.

Lymphatic vessels in the rat heart visible in red by immunofluorescence © Inserm, Ebba Brakenhielm
When the heart is no longe...
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