Euan Ashley and his colleagues discovered an association between heart failure and a pathway linked to narcolepsy. Mark Tuschman
The gene identified by Stanford researchers codes for a protein first identified when a mutated form was shown to cause narcolepsy.
Caring for patients with heart failure costs the US $40 billion a year. Few new treatments have been developed, and those that exist produce varied responses among patients. One major challenge to the development of new treatments has been the lack of genes that can be confidently associated with heart failure. Prof. Euan Ashley is hopeful that the new finding will open doors to evaluating possible treatments.
orexin (hypocretin) neuropeptide precursor
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