A multi-institution study led by Rohan Dharmakumar, PhD, of Indiana University School of Medicine, has identified that iron drives the formation of fatty tissue in the heart and leads to chronic heart failure in about fifty percent of heart attack survivors. The discovery, recently published in Nature Communications, paves the way for treatments that have the potential to prevent heart failure in nearly half a million people a year in the United States, and many millions more worldwide.
“For the first time, we have identified a root cause of chronic heart failure following a heart attack,” Dharmakumar said.
Dharmakumar is executive director of IU’s Krannert Cardiovascular Researc...
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