Discovery opens new possibilities for treating COVID-19 by disrupting virus’ ability to bind the carbohydrate, potentially by using a repurposed drug. Researchers discovered that the SARS-CoV-2 virus can’t grab hold of cell receptor ACE2 without a carbohydrate called heparan sulfate, which is also found on lung cell surfaces – disrupting that interaction with a repurposed drug may help treat COVID-19.
A molecule known as ACE2 sits like a doorknob on the outer surfaces of the cells that line the lungs...
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