hepatic stellate cells tagged posts

TRAF6 is required for skeletal muscle regeneration.

Salk team develops Drug that prevents, reverses deadly liver damage in mice. Chronic damage to the liver eventually creates a wound that never heals. This condition, called fibrosis, gradually replaces normal liver cells -which detoxify the food and liquid we consume – with more and more scar tissue until the organ no longer works.

Scientists at the Salk Institute have identified a drug that halts this unchecked accumulation of scar tissue in the liver. The small molecule, called JQ1, prevented as well as reversed fibrosis in animals and could help the millions of people worldwide affected by liver fibrosis and cirrhosis, caused by alcoholism and diseases like hepatitis.

“After too much damage in the liver, the scar tissue itself causes m...