High affinity natural killer cells (haNKs) tagged posts

Engineered Killer Immune Cells Target Tumors and their Immunosuppressive Allies

D-L1 CAR haNKs demonstrated superior killing of murine HNSCC targets compared to haNKs.

Scientists have engineered natural killer immune cells that not only kill head and neck tumour cells in mice but also reduce the immune-suppressing myeloid cells that allow tumours to evade the immune response, according to a new study in eLife.

The engineered cell therapy could be used as an alternative approach for treating cancer in patients for whom previous immunotherapy based on the activation of T cells has failed. These findings are reported by researchers at the U.S. National Institutes of Health (NIH) in Bethesda, Maryland.

In recent years, treatments called T-cell therapy or CAR-T cell therapy have been approved to treat blood cancers, and many others are now in development for othe...

Read More