high-fat and high-fructose (HFFD)-induced insulin resistance and cognitive impairment tagged posts

Green tea. Credit: © KMNPhoto / Fotolia

New research identifies potential therapeutic intervention for memory impairment, neuroinflammation, and brain insulin resistance induced by high-fat, high-fructose diet. A study published online in The FASEB Journal, involving mice, suggests that EGCG (epigallocatechin-3-gallate), the most abundant catechin and biologically active component in green tea, could alleviate high-fat and high-fructose (HFFD)-induced insulin resistance and cognitive impairment. Previous research pointed to the potential of EGCG to treat a variety of human diseases, yet until now, EGCG’s impact on insulin resistance and cognitive deficits triggered in the brain by a Western diet remained unclear.

“Green tea is the second most consumed beverage in the world after water, an...