hippocampus tagged posts

One Simple Brain Hack might Boost Learning and Improve Mental Health

Shifting from a high-pressure mindset to a curious one improves people’s memory.

New research from Duke found that people who imagined being a thief scouting a virtual art museum in preparation for a heist were better at remembering the paintings they saw, compared to people who played the same computer game while imagining that they were executing the heist in-the-moment.

These subtle differences in motivation—urgent, immediate goal-seeking versus curious exploration for a future goal—have big potential for framing real-world challenges such as encouraging people to get a vaccine, prompting climate change action, and even treating psychiatric disorders.

The findings appeared online July 25 in the Proceedings of the National Academy of Sciences.

Alyssa Sinclair, Ph.D...

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Low-Flavanol Diet drives Age-related Memory Loss, Large Study finds

A large-scale study led by researchers at Columbia and Brigham and Women’s Hospital/Harvard is the first to establish that a diet low in flavanols—nutrients found in certain fruits and vegetables—drives age-related memory loss.

The study found that flavanol intake among older adults tracks with scores on tests designed to detect memory loss due to normal aging and that replenishing these bioactive dietary components in mildly flavanol-deficient adults over age 60 improves performance on these tests.

“The improvement among study participants with low-flavanol diets was substantial and raises the possibility of using flavanol-rich diets or supplements to improve cognitive function in older adults,” says Adam Brickman, Ph.D...

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Memories could be lost if Two Key Brain Regions Fail to Sync together, study finds

Neurons brain cells

Learning, remembering something, and recalling memories is supported by multiple separate groups of neurons connected inside and across key regions in the brain. If these neural assemblies fail to sync together at the right time, the memories are lost, a new study led by the universities of Bristol and Heidelberg has found.

How do you keep track of what to do next? What happens in the brain when your mind goes blank? Short-term memory relies on two key brain regions: the hippocampus and the prefrontal cortex. The researchers set out to establish how these brain regions interact with one another as memories are formed, maintained and recalled at the level of specific groups of neurons. The study, published in Current Biology, also wanted to understand why memory sometimes fails.

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Human-approved Medication Brings Back ‘Lost’ Memories in Mice

Human-approved medication brings back 'lost' memories in mice
High magnification image showing part of the mouse hippocampus in which a sparse population of neurons encoding a specific learning event are labelled in red. Neurons that are not activated by the learning event are shown in blue. | Illustration Havekes Lab, University of Groningen

Students sometimes pull an all-nighter to prepare for an exam. However, research has shown that sleep deprivation is bad for your memory. Now, University of Groningen neuroscientist Robbert Havekes discovered that what you learn while being sleep deprived is not necessarily lost, it is just difficult to recall.

Together with his team, he has found a way to make this “hidden knowledge” accessible again days after studying while sleep-deprived using optogenetic approaches, and the human-approved asthma drug...

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