ZMYND8 has demonstrated its ability to block metastasis-linked genes in prostate cancer, according to a study at The University of Texas MD Anderson Cancer Center. “These findings are important as cancer metastasis is a complicated process and is both devastating and clinically challenging,” said Min Gyu Lee, Ph.D., associate professor of Molecular and Cellular Oncology.
Alterations in histone modifications, including acetylation and methylation, are frequently associated with cancer development. Lee’s group looked at ZMYND8 as a histone “reader” that could possibly impact gene expression by recognizing these histone modifications known as histone “marks.”
“It has been well documented that the effects of histone acetylation and methyl...
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