HIV Eliminated tagged posts

HIV Eliminated from the Genomes of Living Animals

A working model for HIV-1 elimination. A cartoon illustration of the viral elimination strategy is shown for single LASER ART, AAV9-CRISPR-Cas9 injection groups and dual treatment groups. We highlight the observed restriction of viral infection by LASER ART and an inability to achieve elimination of virus by AAV9-CRISPR-Cas9 treatment alone. However, the sequential administration of LASER ART and AAV9-CRISPR-Cas9 can achieve viral elimination in a subset of animals. Why specific animals are cured of infection while others are not is incompletely understood but tied, in measure, to viral set points

Researchers have for the first time eliminated replication-competent HIV-1 DNA – the virus responsible for AIDS – from the genomes of living animals...

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