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    hormonal signal tagged posts

    Scientists uncover how High-Fat diet drives Colorectal Cancer growth

    February 22, 2019, Categories  Biology/Biotechnology, Health/Medical

    Colon cancer growth, as measured by the number of dividing cells shown in green, is dramatically increased when the FXR-regulated gene network is disrupted by specific bile acids or a high-fat diet.
    Colon cancer growth, as measured by the number of dividing cells shown in green, is dramatically increased when the FXR-regulated gene network is disrupted by specific bile acids or a high-fat diet.
    Click here for a high-resolution image.
    Credit: Salk Institute

    Experimental drug candidate slows cancer progression in mouse model. A new study suggests that high-fat diets fuel colorectal cancer growth by upsetting the balance of bile acids in the intestine and triggering a hormonal signal that lets potentially cancerous cells thrive. The findings could explain why colorectal cancer, which can take decades to develop, is being seen in younger people growing up at a time when higher-fat diets are common.

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