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    Newly discovered compounds help cells fight a wide range of viruses

    July 21, 2025, Categories  Astronomy/Space

    A virus being destroyed by beams of light
    Researchers at MIT and other institutions have discovered broad-spectrum antiviral compounds through the use of a novel optogenetic screen, symbolized in this image by a beam of light piercing a virus.
    Credits:Credit: Kendall Pata, Type A Creative; edited by MIT News

    Researchers at MIT and other institutions have identified compounds that can fight off viral infection by activating a defense pathway inside host cells. These compounds, they believe, could be used as antiviral drugs that work against not just one but any kind of virus.

    The researchers identified these compounds, which activate a host cell defense system known as the integrated stress response pathway, in a screen of nearly 400,000 molecules...

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