Computer-designed customized regenerative heart valve. Credit: Image adapted from figure in publication
Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time. Tissue engineering, which involves growing replacement parts in the laboratory, forms a key part of this research. The parts can be used to replace defective cells and tissues in the body and restore their normal functioning. The bioengineered replacements have significant advantages over the artificial implants currently in use: They do not cause immune reactions in the patient’s body, and they can grow and regenerate themselves.
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