human pluripotent stem cells tagged posts

Human intestinal organoids (HIOs) generated in the hydrogel matrix differentiate into mature intestinal tissue and present specialized human intestinal cell types, such as enteroendocrine cells (CHGA; red), after transplantation into an animal. Credit: Ricardo Cruz-Acuña, Georgia Tech

By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids – made from human pluripotent stem cells – researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD)...