hydrogel tagged posts

Bonding to Bones Strongly

The DN gel and HAp/DN gel implanted in rabbit femurs. The Micro-CT image shows HAp/DN gel has the same contrast as the bone HAp (indicated with the red arrow); the cross-section shows that the boundaries of the bone and the HAp layer are fused. Credit: Nonoyama T., Wada S. et al., Advanced Materials, May 17, 2016

The DN gel and HAp/DN gel implanted in rabbit femurs. The Micro-CT image shows HAp/DN gel has the same contrast as the bone HAp (indicated with the red arrow); the cross-section shows that the boundaries of the bone and the HAp layer are fused. Credit: Nonoyama T., Wada S. et al., Advanced Materials, May 17, 2016

Researchers at Hokkaido University have developed a new kind of hydrogel that bonds spontaneously and strongly to defected bones, suggesting potential use in the treatments of joint injuries. When soft supporting human tissues – including cartilage and ligaments, which are joined firmly to bones – are damaged, they cannot spontaneously repair inside the body. The use of artificial supporting tissues has the potential to significantly ameliorate damage to soft tissues...

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‘Missing Tooth’ Hydrogels handle Hard-to-deliver Drugs

A hydrogel made at Rice University consists of custom peptide fibers with spaces - "missing teeth" - that can trap and deliver hydrophobic small-molecule drugs. Credit: I-Che Li/Rice University

A hydrogel made at Rice University consists of custom peptide fibers with spaces – “missing teeth” – that can trap and deliver hydrophobic small-molecule drugs. Credit: I-Che Li/Rice University

Custom hydrogel traps water-avoiding molecules for slow delivery. A gap-toothed peptide created by bioengineers at Rice University may be an efficient way to deliver insoluble drugs to precise locations in the body. Rice bioengineer Jeffrey Hartgerink and his students made a hydrogel of what they call “missing tooth” peptide nanofibers. Gaps in the fibers are designed to hold drug molecules that have hydrophobic properties. The biodegradable gel can be injected where needed and releases the medication over time.

Hydrogels built of custom peptides are a specialty of Hartgerink’s lab, which has introd...

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New Synthetic Models with Electromagnetic Properties of Human Tissues

Phantom Patent UPV

UPV researchers have developed new synthetic models of human tissues that simulate electromagnetic properties of different tissues and organs. Known as phantoms, these models may be of interest for the development of new technologies for use in medical screening and evaluation of 5G mobile communication devices.

Recently, there has been a growing interest in the use of telecomms devices for clinical diagnosis. Tiny sensors and monitoring units can be incorporated into capsules and ingested orally, recording biological data inside the body and transmitting it to the outside. These devices communicate wirelessly, sending electromagnetic waves through the body, which acts as a transmission medium...

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New Mussel-Inspired Surgical Protein Glue: Close Wounds, Open Medical possibilities

Prof. Hyung Joon Cha and his colleagues at POSTECH have developed new tissue adhesive that is mussel-protein based via a photochemical reaction using blue visible light. Myriad medical #applications including sutureless wound closures of delicate organs or tissues beyond surgeons' reach.

Prof. Hyung Joon Cha and his colleagues at POSTECH have developed new tissue adhesive that is mussel-protein based via a photochemical reaction using blue visible light. Myriad medical #applications including sutureless wound closures of delicate organs or tissues beyond surgeons’ reach.

Inspired by nature’, a new light-activated adhesive hydrogel has been developed. The innovative surgical protein glue, called LAMBA, not only closes an open wound on a wet bleeding site within less than 60 seconds but also effectively facilitates the healing process without inflammation or a scar. It works on the same principles as mussels attaching to underwater surfaces and insects maintaining structural balance and flexibility...

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