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Scientists Uncover New way to Defeat Therapy-Resistant Prostate Cancer

Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia

Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia

A new study led by scientists from TSRI, Florida sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer. Targeting the components of this circuit suppresses advanced prostate cancer development. Prostate cancer—which, according to the American Cancer Society, affects 1 in 6 American men—is the second-leading cause of death after lung cancer in American men.

Currently, the most effective treatment of advanced prostate cancer is to deprive the cancer of what feeds it—androgen hormones such as testosterone...

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